|Application ||WB, IHC-P, E|
|Other Accession||B9EKX1, NP_997382.2, NP_001013754.3|
|Calculated MW||96371 Da|
|Antigen Region||563-591 aa|
|Other Names||Patched domain-containing protein 4, PTCHD4, C6orf138|
|Target/Specificity||This C6orf138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the Central region of human C6orf138.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C6orf138 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down- regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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