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COG3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96JB2 |
| Other Accession | Q8CI04, NP_113619.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 94096 Da |
| Antigen Region | 666-695 aa |
| Gene ID | 83548 |
|---|---|
| Other Names | Conserved oligomeric Golgi complex subunit 3, COG complex subunit 3, Component of oligomeric Golgi complex 3, Vesicle-docking protein SEC34 homolog, p94, COG3, SEC34 |
| Target/Specificity | This COG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human COG3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | COG3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | COG3 |
|---|---|
| Synonyms | SEC34 |
| Function | Involved in ER-Golgi transport. |
| Cellular Location | Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the peripheral membrane of cis/medial cisternae |
| Tissue Location | Widely expressed with highest levels in pancreas and testis and lowest levels in lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles. [provided by RefSeq].
References
Laufman, O., et al. EMBO J. 28(14):2006-2017(2009)
Shestakova, A., et al. Traffic 7(2):191-204(2006)
Loh, E., et al. J. Biol. Chem. 279(23):24640-24648(2004)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
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