|Application ||WB, E|
|Other Accession||Q8CI04, NP_113619.1|
|Calculated MW||94096 Da|
|Antigen Region||666-695 aa|
|Other Names||Conserved oligomeric Golgi complex subunit 3, COG complex subunit 3, Component of oligomeric Golgi complex 3, Vesicle-docking protein SEC34 homolog, p94, COG3, SEC34|
|Target/Specificity||This COG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human COG3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||COG3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in ER-Golgi transport.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the peripheral membrane of cis/medial cisternae|
|Tissue Location||Widely expressed with highest levels in pancreas and testis and lowest levels in lung|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles. [provided by RefSeq].
Laufman, O., et al. EMBO J. 28(14):2006-2017(2009)
Shestakova, A., et al. Traffic 7(2):191-204(2006)
Loh, E., et al. J. Biol. Chem. 279(23):24640-24648(2004)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
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