SMTNL1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
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Primary Accession | A8MU46 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52987 Da |
Antigen Region | 130-159 aa |
Gene ID | 219537 |
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Other Names | Smoothelin-like protein 1, SMTNL1 |
Target/Specificity | This SMTNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human SMTNL1. |
Dilution | WB~~1:2000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SMTNL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SMTNL1 |
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Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). |
Cellular Location | Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity) Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). |
Tissue Location | Expressed in striated muscles, specifically in type 2a fibers (at protein level). |
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