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FOXI3 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FOXI3 Antibody (Center) AP11492c
    FOXI3 Antibody (Center) (Cat. #AP11492c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FOXI3 antibody detected the FOXI3 protein (arrow).
    detail
  • FC - FOXI3 Antibody (Center) AP11492c
    FOXI3 Antibody (Center) (Cat. #AP11492c) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession A8MTJ6
Other Accession NP_001129121.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 43326 Da
Antigen Region 157-186 aa
Additional Information
Gene ID 344167
Other Names Forkhead box protein I3, FOXI3
Target/Specificity This FOXI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human FOXI3.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOXI3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXI3 {ECO:0000303|PubMed:36260083, ECO:0000312|HGNC:HGNC:35123}
Function Transcription factor required for pharyngeal arch development, which is involved in hair, ear, jaw and dental development (PubMed:37041148). May act as a pioneer transcription factor during pharyngeal arch development (By similarity). Required for epithelial cell differentiation within the epidermis (By similarity). Acts at multiple stages of otic placode induction: necessary for preplacodal ectoderm to execute an inner ear program (By similarity). Required for hair follicle stem cell specification (By similarity). Acts downstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch (By similarity).
Cellular Location Nucleus.
Citations (0)
citation

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Background

Possible transcriptional factor (By similarity).

References

Drogemuller, C., et al. Science 321 (5895), 1462 (2008) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)

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$ 365.00
$ 140.00
Cat# AP11492c
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