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Myeloperoxidase Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Myeloperoxidase Antibody (N-term) AP11560A
    Myeloperoxidase Antibody (N-term) (Cat. #AP11560a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Myeloperoxidase antibody detected the Myeloperoxidase protein (arrow).
  • FC - Myeloperoxidase Antibody (N-term) AP11560A
    Myeloperoxidase Antibody (N-term) (Cat. #AP11560a) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05164
Other Accession NP_000241.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 83869 Da
Antigen Region 60-89 aa
Additional Information
Gene ID 4353
Other Names Myeloperoxidase, MPO, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
Target/Specificity This Myeloperoxidase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human Myeloperoxidase.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMyeloperoxidase Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPO
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Cellular Location Lysosome.
Research Areas
Citations (0)

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Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].


Banerjee, M., et al. Toxicol. Appl. Pharmacol. 249(1):47-54(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Nahon, P., et al. Antioxid. Redox Signal. (2010) In press :
Wang, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 30(4):437-442(2010)
Hua, F., et al. Zhongguo Fei Ai Za Zhi 13(2):122-127(2010)

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Cat# AP11560A
(40 western blots)
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