|Application ||WB, IHC-P, E|
|Calculated MW||136653 Da|
|Antigen Region||596-625 aa|
|Other Names||SAM and SH3 domain-containing protein 1, Proline-glutamate repeat-containing protein, SASH1, KIAA0790, PEPE1|
|Target/Specificity||This SASH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 596-625 amino acids from the Central region of human SASH1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SASH1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a role in a signaling pathway. Could act as a tumor suppressor.|
|Tissue Location||Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
SASH1 may have a role in a signaling pathway and could act as a tumor suppressor.
Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Fellay, J., et al. PLoS Genet. 5 (12), E1000791 (2009) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Heinzen, E.L., et al. J. Alzheimers Dis. (2009) In press :
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