|Application ||WB, IHC-P, E|
|Calculated MW||136653 Da|
|Antigen Region||596-625 aa|
|Other Names||SAM and SH3 domain-containing protein 1, Proline-glutamate repeat-containing protein, SASH1, KIAA0790, PEPE1|
|Target/Specificity||This SASH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 596-625 amino acids from the Central region of human SASH1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SASH1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a role in a signaling pathway. Could act as a tumor suppressor.|
|Tissue Location||Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.|
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Provided below are standard protocols that you may find useful for product applications.
SASH1 may have a role in a signaling pathway and could act as a tumor suppressor.
Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Fellay, J., et al. PLoS Genet. 5 (12), E1000791 (2009) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Heinzen, E.L., et al. J. Alzheimers Dis. (2009) In press :
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