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SCEL Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SCEL Antibody (Center) AP11564c
    SCEL Antibody (Center) (Cat. #AP11564c) western blot analysis in NCI-H292,A549 cell line lysates (35ug/lane).This demonstrates the SCEL antibody detected the SCEL protein (arrow).
  • FC - SCEL Antibody (Center) AP11564c
    SCEL Antibody (Center) (Cat. #AP11564c) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95171
Other Accession NP_659001.2, NP_003834.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 77552 Da
Antigen Region 260-289 aa
Additional Information
Gene ID 8796
Other Names Sciellin, SCEL
Target/Specificity This SCEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-289 amino acids from the Central region of human SCEL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSCEL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope.
Cellular Location Cytoplasm. Membrane. Note=May become cross- linked to membrane proteins by transglutaminase
Tissue Location Highly expressed in esophagus. It is also expressed in keratinocytes, amniotic tissue, foreskin stratum spinosum and stratum granulosum, hair follicle and nail
Research Areas
Citations (0)

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The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.


Pyle, A.L., et al. Cardiovasc. Pathol. 19 (2), E13-E20 (2010) :
Corona, W., et al. Anticancer Res. 24 (3A), 1417-1419 (2004) :
Champliaud, M.F., et al. J. Invest. Dermatol. 121(4):781-785(2003)
Champliaud, M.F., et al. Genomics 70(2):264-268(2000)
Champliaud, M.F., et al. J. Biol. Chem. 273(47):31547-31554(1998)

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$ 295.00
$ 99.00
Cat# AP11564c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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