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SMYD4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q8IYR2 |
| Other Accession | NP_443160.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 89225 Da |
| Antigen Region | 541-568 aa |
| Gene ID | 114826 |
|---|---|
| Other Names | SET and MYND domain-containing protein 4, 211-, SMYD4, KIAA1936 |
| Target/Specificity | This SMYD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-568 amino acids from the C-terminal region of human SMYD4. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SMYD4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SMYD4 |
|---|---|
| Synonyms | KIAA1936 |
| Function | Plays a critical role in cardiac development (PubMed:30110327). Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1 (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8BTK5}. Cytoplasm {ECO:0000250|UniProtKB:Q8BTK5} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of the protein remains unknown.
References
O'Seaghdha, C.M., et al. Hum. Mol. Genet. 19(21):4296-4303(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hu, L., et al. Cancer Res. 69(9):4067-4072(2009)
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