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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLEC12B Antibody (C-term)   

CLEC12B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CLEC12B Antibody (C-term) AP11585b
    CLEC12B Antibody (C-term) (Cat. #AP11585b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CLEC12B antibody detected the CLEC12B protein (arrow).
  • WB - CLEC12B Antibody (C-term) AP11585b
    CLEC12B Antibody (C-term) (Cat. #AP11585b) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the CLEC12B antibody detected the CLEC12B protein (arrow).
  • IHC-P - CLEC12B Antibody (C-term) AP11585b
    CLEC12B Antibody (C-term) (Cat. #AP11585b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLEC12B Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q2HXU8
Other Accession NP_001123470.1, NP_995324.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31616 Da
Antigen Region 249-276 aa
Additional Information
Gene ID 387837
Other Names C-type lectin domain family 12 member B, Macrophage antigen H, CLEC12B
Target/Specificity This CLEC12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-276 amino acids from the C-terminal region of human CLEC12B.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLEC12B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC12B
Function Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis
Research Areas
Citations (0)

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Background

Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.

References

Hoffmann, S.C., et al. J. Biol. Chem. 282(31):22370-22375(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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Cat# AP11585b
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