|Application ||WB, IHC-P, E|
|Other Accession||NP_001123470.1, NP_995324.2|
|Calculated MW||31616 Da|
|Antigen Region||249-276 aa|
|Other Names||C-type lectin domain family 12 member B, Macrophage antigen H, CLEC12B|
|Target/Specificity||This CLEC12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-276 amino acids from the C-terminal region of human CLEC12B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CLEC12B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis|
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Provided below are standard protocols that you may find useful for product applications.
Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Hoffmann, S.C., et al. J. Biol. Chem. 282(31):22370-22375(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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