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LDLRAD3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q86YD5 |
| Other Accession | NP_777562.1 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37419 Da |
| Antigen Region | 317-345 aa |
| Gene ID | 143458 |
|---|---|
| Other Names | Low-density lipoprotein receptor class A domain-containing protein 3, LDLRAD3 |
| Target/Specificity | This LDLRAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-345 amino acids from the C-terminal region of human LDLRAD3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LDLRAD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LDLRAD3 (HGNC:27046) |
|---|---|
| Synonyms | LRAD3 |
| Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation (PubMed:26854353). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of the protein remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kantojarvi, K., et al. Psychiatr. Genet. 20(3):102-108(2010)
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