KCTD8 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q6ZWB6 |
Other Accession | NP_938167.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52440 Da |
Antigen Region | 434-462 aa |
Gene ID | 386617 |
---|---|
Other Names | BTB/POZ domain-containing protein KCTD8, KCTD8 |
Target/Specificity | This KCTD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-462 amino acids from the C-terminal region of human KCTD8. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KCTD8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KCTD8 |
---|---|
Function | Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). |
Cellular Location | Presynaptic cell membrane. Postsynaptic cell membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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