|Application ||WB, IHC-P, E|
|Calculated MW||52440 Da|
|Antigen Region||434-462 aa|
|Other Names||BTB/POZ domain-containing protein KCTD8, KCTD8|
|Target/Specificity||This KCTD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-462 amino acids from the C-terminal region of human KCTD8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KCTD8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).|
|Cellular Location||Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane|
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Provided below are standard protocols that you may find useful for product applications.
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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