KILLIN Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 3
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | B2CW77 |
Other Accession | NP_001119521.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 19958 Da |
Antigen Region | 136-163 aa |
Gene ID | 100144748 |
---|---|
Other Names | Killin, KLLN |
Target/Specificity | This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN. |
Dilution | WB~~1:500 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KILLIN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KLLN |
---|---|
Function | DNA-binding protein involved in S phase checkpoint control- coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single-stranded DNA. |
Cellular Location | Nucleus. |
Provided below are standard protocols that you may find useful for product applications.
Background
DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
References
Cho, Y.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(14):5396-5401(2008)
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