- CITATIONS: 3
|Application ||WB, E|
|Calculated MW||19958 Da|
|Antigen Region||136-163 aa|
|Other Names||Killin, KLLN|
|Target/Specificity||This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KILLIN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA.|
Provided below are standard protocols that you may find useful for product applications.
DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
Cho, Y.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(14):5396-5401(2008)
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