|Application ||WB, IHC-P, FC, E|
|Other Accession||P19879, NP_148935.1, NP_054776.1|
|Calculated MW||33922 Da|
|Antigen Region||246-276 aa|
|Other Names||Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A|
|Target/Specificity||This OGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the C-terminal region of human OGN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OGN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010) :
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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