|Application ||WB, FC, E|
|Calculated MW||48670 Da|
|Antigen Region||255-284 aa|
|Other Names||Mast cell carboxypeptidase A, MC-CPA, Carboxypeptidase A3, CPA3|
|Target/Specificity||This CPA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from the Central region of human CPA3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPA3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules|
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Provided below are standard protocols that you may find useful for product applications.
Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a form which is obtained as a binary complex of a procarboxypeptidase A with proproteinase E and functions as a secretory granule metalloexopeptidase.
Pejler, G., et al. Trends Immunol. 30(8):401-408(2009)
Chen, Z.Q., et al. World J. Gastroenterol. 10(3):342-347(2004)
Huang, H., et al. Cancer Res. 59(12):2981-2988(1999)
Dikov, M.M., et al. J. Biol. Chem. 269(41):25897-25904(1994)
Natsuaki, M., et al. J. Invest. Dermatol. 99(2):138-145(1992)
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