PAX1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P15863 |
Other Accession | P09084, P47236, NP_006183.2 |
Reactivity | Human |
Predicted | Chicken, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 55499 Da |
Antigen Region | 163-189 aa |
Gene ID | 5075 |
---|---|
Other Names | Paired box protein Pax-1, HuP48, PAX1, HUP48 |
Target/Specificity | This PAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-189 amino acids from the N-terminal region of human PAX1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PAX1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PAX1 |
---|---|
Synonyms | HUP48 |
Function | This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The PAX genes, including PAX1, are a highly conserved family of developmental control genes that encode transcription factors and have been shown to play a role in pattern formation during embryogenesis in vertebrates (McGaughran et al., 2003 [PubMed 12774041]). See PAX7 (MIM 167410) for a discussion of paired box domain genes.
References
Huang, T.H., et al. Int. J. Gynecol. Cancer 20(4):513-519(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Hillmer, A.M., et al. Nat. Genet. 40(11):1279-1281(2008)
Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)
Fei, Q., et al. Zhonghua Yi Xue Za Zhi 88(37):2597-2602(2008)
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