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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TMEM100 Antibody (C-term)   

TMEM100 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMEM100 Antibody (C-term) AP11713b
    TMEM100 Antibody (C-term) (Cat. #AP11713b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TMEM100 antibody detected the TMEM100 protein (arrow).
  • IHC-P - TMEM100 Antibody (C-term) AP11713b
    TMEM100 Antibody (C-term) (Cat. #AP11713b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMEM100 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - TMEM100 Antibody (C-term) AP11713b
    TMEM100 Antibody (C-term) (Cat. #11713b) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NV29
Other Accession Q2KIC8, NP_001093110.1, NP_060756.2
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 14386 Da
Antigen Region 93-122 aa
Additional Information
Gene ID 55273
Other Names Transmembrane protein 100, TMEM100
Target/Specificity This TMEM100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human TMEM100.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMEM100 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM100
Function Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.
Cellular Location Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein Perikaryon. Cytoplasm, perinuclear region. Endoplasmic reticulum Note=Colocalized with HSPA5 in the endoplasmic reticulum (ER) Enriched in ER microsome. Colocalized with BMP4 in neural cell bodies and neural fibers of the enteric nervous system
Tissue Location Expressed in neurons of the myenteric and submucosal plexuses in the gastric body, jejunum and proximal colon. Expressed in arterial endothelial cells and neurons of the central nervous system and peripheral nervous system. Expressed in umbilical artery endothelial cells (at protein level)
Research Areas
Citations (0)

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de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)

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$ 295.00
$ 99.00
Cat# AP11713b
(40 western blots)
Availability: In Stock
Bulk Size
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