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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   LOC129293 Antibody (C-term)   

LOC129293 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LOC129293 Antibody (C-term) AP11741b
    LOC129293 Antibody (C-term) (Cat. #AP11741b) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the LOC129293 antibody detected the LOC129293 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86V40
Other Accession NP_001074293.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57676 Da
Antigen Region 342-371 aa
Additional Information
Gene ID 129293
Other Names Metalloprotease TIKI1, 34--, TRAB domain-containing protein 2A, TRABD2A, C2orf89, TIKI1
Target/Specificity This LOC129293 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human LOC129293.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLOC129293 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C2orf89, TIKI1
Function Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)

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$ 295.00
$ 99.00
Cat# AP11741b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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