|Application ||WB, IHC-P, IF, FC, E|
|Other Accession||Q8BUJ9, Q9BE74, NP_038465.1|
|Calculated MW||94984 Da|
|Antigen Region||635-662 aa|
|Other Names||Low-density lipoprotein receptor-related protein 12, LRP-12, Suppressor of tumorigenicity 7 protein, LRP12, ST7|
|Target/Specificity||This LRP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 635-662 amino acids from the C-terminal region of human LRP12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRP12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.|
|Cellular Location||Membrane; Single-pass type I membrane protein Membrane, coated pit|
|Tissue Location||Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney Expressed at very low levels in a number of tumor-derived cell lines.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants.
Garnis, C., et al. Oncogene 23(14):2582-2586(2004)
Battle, M.A., et al. Biochemistry 42(24):7270-7282(2003)
Qing, J., et al. Oncogene 18(2):335-342(1999)
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