|Application ||WB, IHC-P, IF, FC, E|
|Other Accession||Q8BUJ9, Q9BE74, NP_038465.1|
|Calculated MW||94984 Da|
|Antigen Region||635-662 aa|
|Other Names||Low-density lipoprotein receptor-related protein 12, LRP-12, Suppressor of tumorigenicity 7 protein, LRP12, ST7|
|Target/Specificity||This LRP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 635-662 amino acids from the C-terminal region of human LRP12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRP12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.|
|Cellular Location||Membrane; Single-pass type I membrane protein Membrane, coated pit|
|Tissue Location||Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney Expressed at very low levels in a number of tumor-derived cell lines.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants.
Garnis, C., et al. Oncogene 23(14):2582-2586(2004)
Battle, M.A., et al. Biochemistry 42(24):7270-7282(2003)
Qing, J., et al. Oncogene 18(2):335-342(1999)
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