|Application ||IHC-P, WB, E|
|Other Accession||Q9ER71, NP_065714.1|
|Calculated MW||23821 Da|
|Antigen Region||131-159 aa|
|Other Names||Rho-related GTP-binding protein RhoJ, Ras-like protein family member 7B, Tc10-like GTP-binding protein, RHOJ, ARHJ, RASL7B, RHOI, TCL|
|Target/Specificity||This RHOJ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human RHOJ.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHOJ Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ARHJ, RASL7B, RHOI, TCL|
|Function||GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ARHJ belongs to the Rho family of small GTP-binding proteins. Rho proteins regulate the dynamic assembly of cytoskeletal components for several physiologic processes, such as cell proliferation and motility and the establishment of cell polarity. They are also involved in pathophysiologic process, such as cell transformation and metastasis.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Nishikimi, A., et al. FEBS Lett. 579(5):1039-1046(2005)
Ruusala, A., et al. FEBS Lett. 572 (1-3), 159-166 (2004) :
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