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SOX1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | O00570 |
| Other Accession | Q9DDD7, P47792, Q6EJB7, P48433, Q5FWM3, P55863, O42569, P48432, P48431, Q6P0E1, P48430, Q2PG84, P53783, O57401, Q2Z1R2, Q6DGL6, B0ZTE2, Q04892, P61259, O95416, Q32PP9, Q9W7R6, NP_005977.2, P54231 |
| Reactivity | Human |
| Predicted | Chicken, Zebrafish, Monkey, Mouse, Xenopus, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39023 Da |
| Antigen Region | 47-76 aa |
| Gene ID | 6656 |
|---|---|
| Other Names | Transcription factor SOX-1, SOX1 |
| Target/Specificity | This SOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human SOX1. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SOX1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOX1 |
|---|---|
| Function | Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Mainly expressed in the developing central nervous system |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
References
Panayi, H., et al. J. Neurosci. 30(37):12274-12280(2010)
Phi, J.H., et al. J Neurosurg Pediatr 5(6):608-614(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Titulaer, M.J., et al. J. Clin. Oncol. 27(26):4260-4267(2009)
Stolk, L., et al. Nat. Genet. 41(6):645-647(2009)
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