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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   S100A1 Antibody (C-term)   

S100A1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - S100A1 Antibody (C-term) AP11779b
    S100A1 Antibody (C-term) (Cat. #AP11779b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the S100A1 antibody detected the S100A1 protein (arrow).
  • IHC-P - S100A1 Antibody (C-term) AP11779b
    S100A1 Antibody (C-term) (Cat. #AP11779b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of S100A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23297
Other Accession P02639, NP_006262.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 10546 Da
Antigen Region 45-75 aa
Additional Information
Gene ID 6271
Other Names Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100A1, S100A
Target/Specificity This S100A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-75 amino acids from the C-terminal region of human S100A1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsS100A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S100A1
Synonyms S100A
Function Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Cellular Location Cytoplasm.
Tissue Location Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.


Marlatt, N.M., et al. Protein Expr. Purif. 73(1):58-64(2010)
van Dieck, J., et al. FEBS Lett. 584(15):3269-3274(2010)
Sviatoha, V., et al. Melanoma Res. 20(2):118-125(2010)
DeRycke, M.S., et al. Am. J. Clin. Pathol. 132(6):846-856(2009)
Yusenko, M.V., et al. Int. J. Biol. Sci. 5(6):517-527(2009)

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$ 295.00
$ 99.00
Cat# AP11779b
(40 western blots)
Availability: In Stock
Bulk Size
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