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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   AGBL5 Antibody (N-term)   

AGBL5 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AGBL5 Antibody (N-term) AP11785A
    AGBL5 Antibody (N-term) (Cat. #AP11785a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AGBL5 antibody detected the AGBL5 protein (arrow).
  • IHC-P - AGBL5 Antibody (N-term) AP11785A
    AGBL5 Antibody (N-term) (Cat. #AP11785a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AGBL5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - AGBL5 Antibody (N-term) AP11785A
    Confocal immunofluorescent analysis of AGBL5 Antibody (N-term)(Cat#AP11785a) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NDL9
Other Accession Q58CX9, NP_068603.4
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 97534 Da
Antigen Region 99-127 aa
Additional Information
Gene ID 60509
Other Names Cytosolic carboxypeptidase-like protein 5, 3417-, ATP/GTP-binding protein-like 5, AGBL5, CCP5
Target/Specificity This AGBL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-127 amino acids from the N-terminal region of human AGBL5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGBL5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGBL5
Synonyms CCP5
Function Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post- translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6.
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09M02}. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Mainly cytoplasmic. Slight accumulation in the nucleus is observed (By similarity) Colocalizes with alpha-tubulin in the mitotic spindle and with midbody microtubules in the intercellular bridges formed during cytokinesis. {ECO:0000250|UniProtKB:Q09M02, ECO:0000269|PubMed:23085998}
Tissue Location Expressed in brain.
Research Areas
Citations (0)

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AGBL5 has a function in the processing of cytosolic proteins such as alpha tubulin, which is known to be modified by the removal of a C terminal tyrosine. It is expressed in the brain. There are three named isoforms.


Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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$ 295.00
$ 99.00
Cat# AP11785A
(40 western blots)
Availability: In Stock
Bulk Size
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