|Application ||WB, IHC-P, E|
|Calculated MW||106374 Da|
|Antigen Region||398-425 aa|
|Other Names||Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107, NUP107|
|Target/Specificity||This NUP107 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-425 amino acids from the Central region of human NUP107.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NUP107 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.|
|Cellular Location||Nucleus membrane Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755)|
|Tissue Location||Ubiquitously expressed in fetal and adult tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Kim, S.Y., et al. Biochem. Biophys. Res. Commun. 401(1):131-136(2010)
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Mishra, R.K., et al. Nat. Cell Biol. 12(2):164-169(2010)
Platani, M., et al. Mol. Biol. Cell 20(24):5260-5275(2009)
Whittle, J.R., et al. J. Biol. Chem. 284(41):28442-28452(2009)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.