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CBLN2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CBLN2 Antibody  (C-term) AP11835b
    CBLN2 Antibody (C-term) (Cat. #AP11835b) western blot analysis in mouse brain tissue and MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CBLN2 antibody detected the CBLN2 protein (arrow).
    detail
  • IHC-P - CBLN2 Antibody  (C-term) AP11835b
    CBLN2 Antibody (C-term) (Cat. #AP11835b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CBLN2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8IUK8
Other Accession P98087, Q8BGU2, NP_872317.1
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 24084 Da
Antigen Region 179-207 aa
Additional Information
Gene ID 147381
Other Names Cerebellin-2, CBLN2
Target/Specificity This CBLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human CBLN2.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCBLN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBLN2
Function Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity). Essential for long-term maintenance but not establishment of excitatory synapses (By similarity).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q8BGU2}.
Research Areas
Citations (0)
citation

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Background

CBLN2, Cerebellin 2, is a secreted glycoprotein and, like Cerebellin 1, may also serve as transneuronal regulators of synaptic functions in various brain regions.

References

Grant, S.F., et al. J. Pediatr. 155(6):909-913(2009)
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Kavety, B., et al. Brain Res. Mol. Brain Res. 27(1):152-156(1994)

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$ 365.00
$ 140.00
Cat# AP11835b
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