CBLN2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8IUK8 |
Other Accession | P98087, Q8BGU2, NP_872317.1 |
Reactivity | Human, Mouse |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 24084 Da |
Antigen Region | 179-207 aa |
Gene ID | 147381 |
---|---|
Other Names | Cerebellin-2, CBLN2 |
Target/Specificity | This CBLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human CBLN2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CBLN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CBLN2 |
---|---|
Function | Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity). Essential for long-term maintenance but not establishment of excitatory synapses (By similarity). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q8BGU2}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CBLN2, Cerebellin 2, is a secreted glycoprotein and, like Cerebellin 1, may also serve as transneuronal regulators of synaptic functions in various brain regions.
References
Grant, S.F., et al. J. Pediatr. 155(6):909-913(2009)
Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Kavety, B., et al. Brain Res. Mol. Brain Res. 27(1):152-156(1994)
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