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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDE1B Antibody (C-term)   

PDE1B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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Ordering Information
Catalog # SizeAvailability Price  
AP11846B 400 µl
(40 western blots)
In Stock $ 265.00 Add to cart
AP11846B-ev 80 µl
(8 western blots)
In Stock $ 95.00 Add to cart
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PDE1B Antibody (C-term) - Product Information

  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • ICC=Immunocytochemistry
  • CHIP=Chromatin Immunoprecipitation
  • IHCF=Immunohistochemistry (Frozen Sections)
  • FA=Fluorescence Assay
  • IHCP=Immunohistochemistry (Paraffin-embedded Sections)
  • IC=Immunochemistry
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary AccessionQ01064
Other AccessionNP_000915.1, NP_001159447.1
Isotype Rabbit Ig
Calculated MW 61380 Da
Antigen Region 473-500 aa

PDE1B Antibody (C-term) - Additional Information

Gene ID 5153
Other Names
Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B
This PDE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human PDE1B.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PDE1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

PDE1B Antibody (C-term) - Protein Information

Name PDE1B
Synonyms PDE1B1, PDES1B
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
Cellular Location

PDE1B Antibody (C-term) - Related Products

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AO1827a: PDE1B Antibody

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AO1833a: PDE1B Antibody

AO1834a: PDE1B Antibody

PDE1B Antibody (C-term) - Research Areas

Application Data

  • WB - PDE1B Antibody (C-term) AP11846B

    PDE1B Antibody (C-term) (Cat. #AP11846b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the PDE1B antibody detected the PDE1B protein (arrow).

  • IHC - PDE1B Antibody (C-term) AP11846B

    PDE1B Antibody (C-term) (Cat. #AP11846b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDE1B Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

  • WB - PDE1B Antibody (C-term) AP11846B
  • IHC - PDE1B Antibody (C-term) AP11846B

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Provided below are standard protocols that you may find useful for product applications.


Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).


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Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Vandeput, F., et al. J. Biol. Chem. 282(45):32749-32757(2007)
Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 103(2):460-465(2006)
Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 102(2):497-502(2005)