PDE1B Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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(40 western blots)
|In Stock||$ 265.00||Add to cart|
(8 western blots)
|In Stock||$ 95.00||Add to cart|
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PDE1B Antibody (C-term) - Product Information
|Application ||WB, IHC|
|Other Accession||NP_000915.1, NP_001159447.1|
|Calculated MW||61380 Da|
|Antigen Region||473-500 aa|
PDE1B Antibody (C-term) - Additional Information
|Gene ID 5153|
PDE1B; PDE1B1; PDES1B; Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B; 63 kDa Cam-PDE
This PDE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human PDE1B.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PDE1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
PDE1B Antibody (C-term) - Protein Information
|Synonyms PDE1B1, PDES1B|
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
PDE1B Antibody (C-term) - Related Products
PDE1B Antibody (C-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
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Vandeput, F., et al. J. Biol. Chem. 282(45):32749-32757(2007)
Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 103(2):460-465(2006)
Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 102(2):497-502(2005)