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FGF16 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FGF16 Antibody (N-term) AP11862a
    All lanes : Anti-FGF16 Antibody (N-term) at 1:1000 dilution Lane 1: U-2OS whole cell lysate Lane 2: SK-OV-3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • IHC-P - FGF16 Antibody (N-term) AP11862a
    FGF16 Antibody (N-term) (Cat. #AP11862a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGF16 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O43320
Other Accession O54769, Q9ESL8, NP_003859.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23759 Da
Antigen Region 22-50 aa
Additional Information
Gene ID 8823
Other Names Fibroblast growth factor 16, FGF-16, FGF16
Target/Specificity This FGF16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human FGF16.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGF16 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF16
Function Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
Cellular Location Secreted {ECO:0000250|UniProtKB:O54769}.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue.

References

Sofronescu, A.G., et al. Cardiovasc. Res. 87(1):102-110(2010)
Moffa, A.B., et al. J. Cell. Physiol. 210(3):720-731(2007)
Antoine, M., et al. Biochem. Biophys. Res. Commun. 346(1):224-233(2006)
Zhang, X., et al. J. Biol. Chem. 281(23):15694-15700(2006)
Popovici, C., et al. J. Biol. Chem. 279(38):40146-40152(2004)

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$ 365.00
$ 140.00
Cat# AP11862a
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