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GHSR Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - GHSR Antibody (C-term) AP11873b
    GHSR Antibody (C-term) (Cat. #AP11873b)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GHSR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • WB - GHSR Antibody (C-term) AP11873b
    GHSR Antibody (C-term) (Cat. #AP11873b) western blot analysis in NCI-H292 cell line and mouse bladder tissue lysates (35ug/lane).This demonstrates the GHSR antibody detected the GHSR protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92847
Other Accession A5A4K9, Q95254, NP_940799
Reactivity Human, Mouse
Predicted Pig, Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41329 Da
Antigen Region 326-357 aa
Additional Information
Gene ID 2693
Other Names Growth hormone secretagogue receptor type 1, GHS-R, GH-releasing peptide receptor, GHRP, Ghrelin receptor, GHSR
Target/Specificity This GHSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGHSR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Pituitary and hypothalamus.
Research Areas
Citations (0)

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This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Landgren, S., et al. Alcohol. Clin. Exp. Res. 34(9):1519-1524(2010)
Aghajanova, L., et al. Reprod Sci 17(9):823-832(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)

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$ 295.00
$ 99.00
Cat# AP11873b
(40 western blots)
Availability: In Stock
Bulk Size
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