GPM6B Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | Q13491 |
Other Accession | Q9JJK1, NP_005269 |
Reactivity | Human |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 28989 Da |
Antigen Region | 1-30 aa |
Gene ID | 2824 |
---|---|
Other Names | Neuronal membrane glycoprotein M6-b, M6b, GPM6B, M6B |
Target/Specificity | This GPM6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GPM6B. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GPM6B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPM6B |
---|---|
Synonyms | M6B |
Function | May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Note=Colocalizes with SERT at the plasma membrane. |
Tissue Location | Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions, such as membrane trafficking and cell-to-cell communication.
References
Fjorback, A.W., et al. J. Mol. Neurosci. 37(3):191-200(2009)
Sebastiani, P., et al. Am. J. Hematol. 83(3):189-195(2008)
Combes, P., et al. Neurogenetics 7(1):31-37(2006)
Henneke, M., et al. Am. J. Med. Genet. A 128A (2), 156-158 (2004) :
Werner, H., et al. Mol. Cell. Neurosci. 18(6):593-605(2001)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.