|Application ||WB, IHC-P, E|
|Calculated MW||41811 Da|
|Antigen Region||293-322 aa|
|Other Names||V-set and immunoglobulin domain-containing protein 1, Cell surface A33 antigen, Glycoprotein A34, VSIG1, GPA34|
|Target/Specificity||This VSIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-322 amino acids from the C-terminal region of human VSIG1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VSIG1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Detected only in stomach mucosa and testis, and to a much lesser level in pancreas (at protein level) Detected in gastric cancers (31%), esophageal carcinomas (50%) and ovarian cancers (23%).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Scanlan, M.J., et al. Cancer Immun. 6, 2 (2006) :
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