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C1QC Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - C1QC Antibody (Center) AP11931C
    C1QC Antibody (Center) (Cat. #AP11931c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the C1QC antibody detected the C1QC protein (arrow).
  • IHC-P - C1QC Antibody (Center) AP11931C
    C1QC Antibody (Center) (Cat. #AP11931c)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of C1QC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - C1QC Antibody (Center) AP11931C
    C1QC Antibody (Center) (Cat. #AP11931c) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • IF - C1QC Antibody (Center) AP11931C
    Confocal immunofluorescent analysis of C1QC Antibody (Center)(Cat#AP11931c) with WiDr cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02747
Other Accession NP_758957.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25774 Da
Antigen Region 93-120 aa
Additional Information
Gene ID 714
Other Names Complement C1q subcomponent subunit C, C1QC, C1QG
Target/Specificity This C1QC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the Central region of human C1QC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC1QC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1QC
Synonyms C1QG
Function C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Cellular Location Secreted.
Research Areas
Citations (0)

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This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.


Fraser, D.A., et al. J. Immunol. 185(7):3932-3939(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rafiq, S., et al. Clin. Exp. Immunol. 161(2):284-289(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)

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$ 295.00
$ 99.00
Cat# AP11931C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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