|Application ||WB, E|
|Calculated MW||82012 Da|
|Antigen Region||44-72 aa|
|Other Names||von Willebrand factor A domain-containing protein 2, A domain-containing protein similar to matrilin and collagen, AMACO, Colon cancer secreted protein 2, CCSP-2, VWA2, AMACO|
|Target/Specificity||This VWA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human VWA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VWA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expression is generally absent in normal colon and other normal body tissues, but it is induced an average of 78- fold in Stage II, III, and IV colon cancers, as well as in colon adenomas and colon cancer cell lines|
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Provided below are standard protocols that you may find useful for product applications.
VWA2, also named as AMACO and CCSP2, is a novel candidate serological marker of colon neoplasia. VWA2 is found in the media of variesy of established cell lines of both fibroblast and epithelial origin.
Gao, W., et al. Blood 112(5):1713-1719(2008)
Gebauer, J.M., et al. J. Biol. Chem. 283(26):17846-17854(2008)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Xin, B., et al. Oncogene 24(4):724-731(2005)
Eller, E., et al. Ann. N. Y. Acad. Sci. 1037, 145-149 (2004) :
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