|Application ||IF, WB, IHC-P, E|
|Other Accession||P02554, P13602, P32882, Q3KRE8, Q9CWF2, Q6B856, P85108, Q7TMM9, Q4R5B3, Q13885, P09203, NP_821080.1|
|Predicted||Chicken, Monkey, Mouse, Rat, Bovine, Xenopus, Pig|
|Calculated MW||49953 Da|
|Antigen Region||12-39 aa|
|Other Names||Tubulin beta-2B chain, TUBB2B|
|Target/Specificity||This TUBB2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human TUBB2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TUBB2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). TUBB2B is implicated in neuronal migration.|
|Cellular Location||Cytoplasm, cytoskeleton.|
|Tissue Location||High expression in brain.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq].
Xu, W., et al. Mol. Cancer Ther. 8(12):3318-3330(2009)
Jaglin, X.H., et al. Nat. Genet. 41(6):746-752(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Cucchiarelli, V., et al. Cell Motil. Cytoskeleton 65(8):675-685(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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