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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MGP Antibody (Center)   

MGP Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MGP Antibody (Center) AP11953c
    MGP Antibody (Center) (Cat. #AP11953c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MGP antibody detected the MGP protein (arrow).
  • IHC-P - MGP Antibody (Center) AP11953c
    MGP Antibody (Center) (Cat. #AP11953c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - MGP Antibody (Center) AP11953c
    MGP Antibody (Center) (Cat. #AP11953c) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08493
Other Accession NP_000891.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 12353 Da
Antigen Region 37-66 aa
Additional Information
Gene ID 4256
Other Names Matrix Gla protein, MGP, Cell growth-inhibiting gene 36 protein, MGP, MGLAP
Target/Specificity This MGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human MGP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMGP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MGP
Synonyms MGLAP
Function Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Cellular Location Secreted.
Research Areas
Citations ( 0 )


The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene.


Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press :
Bailey, S.D., et al. Diabetes Care (2010) In press :
Parker, B.D., et al. Ann. Intern. Med. 152(10):640-648(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Schurgers, L.J., et al. Clin J Am Soc Nephrol 5(4):568-575(2010)

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$ 295.00
$ 99.00
Cat# AP11953c
(40 western blots)
Availability: In Stock
Bulk Size
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