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MSI1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MSI1 Antibody (N-term) AP11965a
    Western blot analysis of lysate from SH‑SY5Y cell line, using MSI1 Antibody (N-term)(Cat. #AP11965a). AP11965a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • IHC-P - MSI1 Antibody (N-term) AP11965a
    MSI1 Antibody (N-term) (Cat. #AP11965a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MSI1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - MSI1 Antibody (N-term) AP11965a
    MSI1 Antibody (N-term) (Cat. #AP11965a) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43347
Other Accession Q8K3P4, Q61474, NP_002433
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39125 Da
Antigen Region 67-93 aa
Additional Information
Gene ID 4440
Other Names RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
Target/Specificity This MSI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-93 amino acids from the N-terminal region of human MSI1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSI1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSI1
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Research Areas
Citations (0)

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This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.


Fan, L.F., et al. Int J Colorectal Dis 25(1):17-23(2010)
de Sousa Abreu, R., et al. J. Biol. Chem. 284(18):12125-12135(2009)
Murayama, M., et al. J. Gastroenterol. 44(3):173-182(2009)
Gotte, M., et al. J. Pathol. 215(3):317-329(2008)
Sanchez-Diaz, P.C., et al. BMC Cancer 8, 280 (2008) :

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$ 295.00
$ 99.00
Cat# AP11965a
(40 western blots)
Availability: In Stock
Bulk Size
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