|Application ||WB, IHC-P, IF, E|
|Calculated MW||46374 Da|
|Antigen Region||7-33 aa|
|Other Names||Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase, FAH|
|Target/Specificity||This FAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human FAH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Liu, J., et al. Hum Brain Mapp 30(1):241-255(2009)
Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)
Bliksrud, Y.T., et al. J. Mol. Med. 83(5):406-410(2005)
Dreumont, N., et al. BMC Mol. Biol. 6 (1), 1 (2005) :
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