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FAH Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • IF - FAH Antibody (N-term) AP11966a
    Confocal immunofluorescent analysis of FAH Antibody (N-term)(Cat#AP11966a) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
    detail
  • WB - FAH Antibody (N-term) AP11966a
    FAH Antibody (N-term) (Cat. #AP11966a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FAH antibody detected the FAH protein (arrow).
    detail
  • IHC-P - FAH Antibody (N-term) AP11966a
    FAH Antibody (N-term) (Cat. #AP11966a)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FAH Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, IHC-P, WB, E
Primary Accession P16930
Other Accession NP_000128
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46374 Da
Antigen Region 7-33 aa
Additional Information
Gene ID 2184
Other Names Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase, FAH
Target/Specificity This FAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human FAH.
Dilution IF~~1:10~50
WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFAH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FAH
Tissue Location Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues
Research Areas
Citations (0)
citation

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Background

This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).

References

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Liu, J., et al. Hum Brain Mapp 30(1):241-255(2009)
Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)
Bliksrud, Y.T., et al. J. Mol. Med. 83(5):406-410(2005)
Dreumont, N., et al. BMC Mol. Biol. 6 (1), 1 (2005) :

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$ 182.50
$ 70.00
Cat# AP11966a
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