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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EDN1 Antibody (C-term)   

EDN1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - EDN1 Antibody (C-term) AP11973b
    EDN1 Antibody (C-term) (Cat. #AP11973b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EDN1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • WB - EDN1 Antibody (C-term) AP11973b
    EDN1 Antibody (C-term) (Cat. #AP11973b) western blot analysis in ZR-75-1,U251,MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the EDN1 antibody detected the EDN1 protein (arrow).
  • IF - EDN1 Antibody (C-term) AP11973b
    Confocal immunofluorescent analysis of EDN1 Antibody (C-term)(Cat#AP11973b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05305
Other Accession NP_001946
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24425 Da
Antigen Region 176-203 aa
Additional Information
Gene ID 1906
Other Names Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
Target/Specificity This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human EDN1.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEDN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDN1
Function Endothelins are endothelium-derived vasoconstrictor peptides.
Cellular Location Secreted.
Tissue Location Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
Research Areas
Citations (0)

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The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.


Gonsalves, C., et al. J. Immunol. 185(10):6253-6264(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Feng, J., et al. Circulation 122 (11 SUPPL), S150-S155 (2010) :
Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)
Kaparianos, A., et al. Eur Rev Med Pharmacol Sci 14(8):705-719(2010)

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$ 295.00
$ 99.00
Cat# AP11973b
(40 western blots)
Availability: In Stock
Bulk Size
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