- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
PCDHB6 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP12006a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12006a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
PCDHB6 Antibody (N-term) - Product info | |
| Application | WB, IHC, IF
|
| Primary Accession | Q9Y5E3 |
| Other Accession | NP_061762.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 87350 Da |
PCDHB6 Antibody (N-term) - Additional info | |
| Gene ID 56130 | |
| Other Names PCDHB6; Protocadherin beta-6 | |
| Target/Specificity This PCDHB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the N-terminal region of human PCDHB6. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 IF~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PCDHB6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
PCDHB6 Antibody (N-term) - Protein Information | |
| Name PCDHB6 | |
| Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain | |
| Cellular Location Cell membrane; Single-pass type I membrane protein (By similarity) | |
PCDHB6 Antibody (N-term) - Related products
PCDHB6 Antibody (N-term) - Application data
-
PCDHB6 Antibody (N-term) (Cat. #AP12006a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PCDHB6 antibody detected the PCDHB6 protein (arrow).
-
PCDHB6 Antibody (N-term) (Cat. #AP12006a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCDHB6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
-
Confocal immunofluorescent analysis of PCDHB6 Antibody (N-term)(Cat#AP12006a) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
PCDHB6 Antibody (N-term) - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
REFERENCES
Frank, M., et al. Curr. Opin. Cell Biol. 14(5):557-562(2002) Vanhalst, K., et al. FEBS Lett. 495 (1-2), 120-125 (2001) : Wu, Q., et al. Genome Res. 11(3):389-404(2001) Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000) Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
