OR2J3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O76001 |
Other Accession | NP_001005216.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34950 Da |
Antigen Region | 247-275 aa |
Gene ID | 442186 |
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Other Names | Olfactory receptor 2J3, Hs6M1-3, Olfactory receptor OR6-16, OR6-6, Olfactory receptor 6-6, OR2J3 |
Target/Specificity | This OR2J3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-275 amino acids from the C-terminal region of human OR2J3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | OR2J3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OR2J3 |
---|---|
Function | Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as 'green grassy' or the smell of 'cut grass'. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
References
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) : Menashe, I., et al. BMC Bioinformatics 7, 393 (2006) : Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004) Fuchs, T., et al. Genomics 80(3):295-302(2002) Glusman, G., et al. Genome Res. 11(5):685-702(2001)
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