|Application ||WB, IHC-P, E|
|Calculated MW||99364 Da|
|Antigen Region||821-850 aa|
|Other Names||Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial, PDPr, PDPR, KIAA1990|
|Target/Specificity||This PDPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-850 amino acids from the C-terminal region of human PDPR.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDPR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
PDPR decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity).
Sugden, M.C., et al. Am. J. Physiol. Endocrinol. Metab. 284 (5), E855-E862 (2003) : Ohara, O., et al. DNA Res. 9(2):47-57(2002) Lawson, J.E., et al. J. Biol. Chem. 272(50):31625-31629(1997)
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