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SLC25A31 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SLC25A31 Antibody (Center) AP12028C
    SLC25A31 Antibody (Center) (Cat. #AP12028c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SLC25A31 antibody detected the SLC25A31 protein (arrow).
  • IHC-P - SLC25A31 Antibody (Center) AP12028C
    SLC25A31 Antibody (Center) (Cat. #AP12028c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC25A31 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - SLC25A31 Antibody (Center) AP12028C
    Confocal immunofluorescent analysis of SLC25A31 Antibody (Center)(Cat#AP12028c) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H0C2
Other Accession Q4R8M0, NP_112581.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35022 Da
Antigen Region 139-167 aa
Additional Information
Gene ID 83447
Other Names ADP/ATP translocase 4, ADP, ATP carrier protein 4, Adenine nucleotide translocator 4, ANT 4, Solute carrier family 25 member 31, Sperm flagellar energy carrier protein, SLC25A31, AAC4, ANT4, SFEC
Target/Specificity This SLC25A31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-167 amino acids from the Central region of human SLC25A31.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC25A31 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC25A31
Synonyms AAC4, ANT4, SFEC
Function Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region
Tissue Location Expressed in brain, liver, sperm and testis.
Research Areas
Citations (0)

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Mitochondrial ADP/ATP carriers, such as SLC25A31, are nuclear-coded mitochondrial proteins that catalyze the exchange of ATP generated in mitochondria by ATP synthase (see MIM 108729) against ADP produced in cytosol by most energy-consuming reactions (Dolce et al., 2005 [PubMed 15670820]).


Gallerne, C., et al. Int. J. Biochem. Cell Biol. 42(5):623-629(2010)
Kim, Y.H., et al. Dev. Biol. 302(2):463-476(2007)
Dolce, V., et al. FEBS Lett. 579(3):633-637(2005)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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Cat# AP12028C
(40 western blots)
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