|Application ||WB, FC, E|
|Calculated MW||35932 Da|
|Antigen Region||166-194 aa|
|Other Names||Retinol dehydrogenase 13, 111-, RDH13|
|Target/Specificity||This RDH13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human RDH13.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RDH13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Does not exhibit retinol dehydrogenase (RDH) activity in vitro.|
|Tissue Location||Expressed mostly in eye, pancreas, placenta and lung. In the retina, detected in the inner segment of the photoreceptor cells. Weak signals were observed in a small population of inner nuclear neurons and the inner plexiform layer|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described.
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
Belyaeva, O.V., et al. FEBS J. 275(1):138-147(2008)
Haeseleer, F., et al. J. Biol. Chem. 277(47):45537-45546(2002)
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