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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CACNG6 Antibody (Center)   

CACNG6 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CACNG6 Antibody (Center) AP12044c
    CACNG6 Antibody (Center) (Cat. #AP12044c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CACNG6 antibody detected the CACNG6 protein (arrow).
  • IHC-P - CACNG6 Antibody (Center) AP12044c
    CACNG6 Antibody (Center) (Cat. #AP12044c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CACNG6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - CACNG6 Antibody (Center) AP12044c
    Confocal immunofluorescent analysis of CACNG6 Antibody (Center)(Cat#AP12044c) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9BXT2
Other Accession Q8VHW3, NP_114103.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28129 Da
Antigen Region 108-136 aa
Additional Information
Gene ID 59285
Other Names Voltage-dependent calcium channel gamma-6 subunit, Neuronal voltage-gated calcium channel gamma-6 subunit, CACNG6
Target/Specificity This CACNG6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the Central region of human CACNG6.
Dilution WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCACNG6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CACNG6
Function Thought to stabilize the calcium channel in an inactivated (closed) state.
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma.

References

Lee, J.S., et al. BMC Med. Genet. 11, 138 (2010) :
Chen, R.S., et al. Cell Biochem. Biophys. 47(2):178-186(2007)
Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :
Burgess, D.L., et al. Genomics 71(3):339-350(2001)

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$ 295.00
$ 99.00
Cat# AP12044c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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