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SH2D4A Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP12049a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12049a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
SH2D4A Antibody (N-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9H788 |
| Other Accession | NP_071354.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 52727 Da |
SH2D4A Antibody (N-term) - Additional info | |
| Gene ID 63898 | |
| Other Names SH2D4A; SH2A; SH2 domain-containing protein 4A; Protein SH(2)A | |
| Target/Specificity This SH2D4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-75 amino acids from the N-terminal region of human SH2D4A. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SH2D4A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SH2D4A Antibody (N-term) - Protein Information | |
| Name SH2D4A | |
| Synonyms PPP1R38, SH2A | |
| Function Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation May play a role in T-cell development and function | |
| Cellular Location Cytoplasm. Note=Located at podocyte foot processes (By similarity) | |
| Tissue Location Ubiquitously expressed. Aberrantly expressed in some cancers | |
SH2D4A Antibody (N-term) - Related products
AP12049a: SH2D4A Antibody (N-term)
RI14835: SH2D4A predesign siRNA
SH2D4A Antibody (N-term) - Application data
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SH2D4A Antibody (N-term) (Cat. #AP12049a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SH2D4A antibody detected the SH2D4A protein (arrow).
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SH2D4A Antibody (N-term) (Cat. #AP12049a)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SH2D4A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
SH2D4A Antibody (N-term) - Research Areas
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BACKGROUND
SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
REFERENCES
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Li, T., et al. BMB Rep 42(8):516-522(2009) Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009) Lapinski, P.E., et al. J. Immunol. 181(3):2019-2027(2008) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
