Kif5C-2 Antibody
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | O60282 |
Other Accession | P28738, NP_004513.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 109495 Da |
Gene ID | 3800 |
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Other Names | Kinesin heavy chain isoform 5C, Kinesin heavy chain neuron-specific 2, KIF5C, KIAA0531, NKHC2 |
Target/Specificity | This KIF5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from human KIF5C. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Kif5C-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KIF5C |
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Synonyms | KIAA0531, NKHC2 |
Function | Microtubule-associated force-producing protein that may play a role in organelle transport. Has ATPase activity (By similarity). Involved in synaptic transmission (PubMed:24812067). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, dendrite. Note=Abundant in distal regions of dendrites. |
Tissue Location | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary |
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Provided below are standard protocols that you may find useful for product applications.
Background
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Wang, X., et al. Cell 136(1):163-174(2009)
Schafer, B., et al. Cell. Mol. Life Sci. 66(2):339-349(2009)
Schafer, B., et al. Biochem. Biophys. Res. Commun. 375(2):179-183(2008)
Cho, K.I., et al. Traffic 8(12):1722-1735(2007)
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