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FTSJ3 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FTSJ3 Antibody (Center) AP12057c
    FTSJ3 Antibody (Center) (Cat. #AP12057c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the FTSJ3 antibody detected the FTSJ3 protein (arrow).
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  • CITATIONS: 1
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8IY81
Other Accession NP_060117.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 96558 Da
Antigen Region 616-646 aa
Additional Information
Gene ID 117246
Other Names pre-rRNA processing protein FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163}, 211- {ECO:0000255|HAMAP-Rule:MF_03163}, 2'-O-ribose RNA methyltransferase SPB1 homolog {ECO:0000255|HAMAP-Rule:MF_03163}, Protein ftsJ homolog 3 {ECO:0000255|HAMAP-Rule:MF_03163}, Putative rRNA methyltransferase 3 {ECO:0000255|HAMAP-Rule:MF_03163}, FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163}
Target/Specificity This FTSJ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 616-646 amino acids from the Central region of human FTSJ3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFTSJ3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163}
Function RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
Cellular Location Nucleus, nucleolus {ECO:0000255|HAMAP- Rule:MF_03163, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:22195017}
Research Areas
Citations ( 0 )

Background

Although the function of this gene is not known, the existence of this gene is supported by mRNA and EST data. A possible function of the encoded protein can be inferred from amino acid sequence similarity to the E.coli FtsJ protein and to a mouse protein possibly involved in embryogenesis.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)

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$ 365.00
$ 140.00
Cat# AP12057c
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