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>   home   >   Products   >   Primary Antibodies   >   PRDM5 (PFM2) Antibody   

PRDM5 (PFM2) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQX1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73090 Da
Additional Information
Gene ID 11107
Other Names PR domain zinc finger protein 5, 211-, PR domain-containing protein 5, PRDM5, PFM2
Target/Specificity This PRDM5 (PFM2) antibody is generated from rabbits immunized with purified recombinant GST fusion protein encoding the N-terminal region of human PRDM5.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRDM5 (PFM2) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM5
Synonyms PFM2
Function Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.
Cellular Location Nucleus
Tissue Location Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues.
Citations ( 0 )


The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis.


Xiao, B., et al., Curr. Opin. Struct. Biol. 13(6):699-705 (2003).
Jiang, G.L., et al., Histol. Histopathol. 15(1):109-117 (2000).

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$ 295.00
Cat# AP1205a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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