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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ZEB2 Antibody (C-term)   

ZEB2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZEB2 Antibody (C-term) AP12086b
    ZEB2 Antibody (C-term) (Cat. #AP12086b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ZEB2 antibody detected the ZEB2 protein (arrow).
  • FC - ZEB2 Antibody (C-term) AP12086b
    ZEB2 Antibody (C-term) (Cat. #AP12086b) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60315
Other Accession Q9R0G7, NP_055610.1, NP_001165124.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 136447 Da
Antigen Region 1078-1105 aa
Additional Information
Gene ID 9839
Other Names Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, SMADIP1, Zinc finger homeobox protein 1b, ZEB2, KIAA0569, SIP1, ZFHX1B, ZFX1B
Target/Specificity This ZEB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1105 amino acids from the C-terminal region of human ZEB2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZEB2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZEB2
Synonyms KIAA0569, SIP1, ZFHX1B, ZFX1B
Function Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin.
Cellular Location Nucleus
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.


Kumar, P.A., et al. J. Biol. Chem. 285(41):31148-31156(2010)
Li, A., et al. Cancer Res. 70(13):5226-5237(2010)
Ohashi, S., et al. Cancer Res. 70(10):4174-4184(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :

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Cat# AP12086b
(40 western blots)
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