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hCG_1645727 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - hCG_1645727 Antibody (C-term) AP12139b
    hCG_1645727 Antibody (C-term) (Cat. #AP12139b) western blot analysis in MDA-MB453,ZR-75-1,MCF-7 cell line lysates (35ug/lane).This demonstrates the hCG_1645727 antibody detected the hCG_1645727 protein (arrow).
    detail
  • IHC-P - hCG_1645727 Antibody (C-term) AP12139b
    hCG_1645727 Antibody (C-term) (Cat. #AP12139b)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of hCG_1645727 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession C9JR72
Other Accession Q8C828, NP_001094832.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 49485 Da
Antigen Region 409-438 aa
Additional Information
Gene ID 390594
Other Names Kelch repeat and BTB domain-containing protein 13, KBTBD13
Target/Specificity This hCG_1645727 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the C-terminal region of human hCG_1645727.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionshCG_1645727 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KBTBD13
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.
Cellular Location Cytoplasm
Tissue Location Expressed in skeletal muscle.
Research Areas
Citations (0)
citation

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Background

The gene belongs to a family of genes encoding proteins containing a BTB domain and several kelch repeats. The BTB domain functions as a protein-protein interaction module, which includes an ability to self-associate or to interact with non-BTB domain-containing proteins. The kelch motif typically occurs in groups of five to seven repeats, and has been found in proteins with diverse functions. Known functions of these family members include transcription regulation, ion channel tetramerization and gating, protein ubiquitination or degradation, and cytoskeleton regulation. The exact function of this family member has yet to be determined.

References

Stogios, P.J., et al. Genome Biol. 6 (10), R82 (2005) :

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$ 365.00
$ 140.00
Cat# AP12139b
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