|Application ||IHC-P, WB, E|
|Other Accession||Q8C828, NP_001094832.1|
|Calculated MW||49485 Da|
|Antigen Region||409-438 aa|
|Other Names||Kelch repeat and BTB domain-containing protein 13, KBTBD13|
|Target/Specificity||This hCG_1645727 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the C-terminal region of human hCG_1645727.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||hCG_1645727 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.|
|Tissue Location||Expressed in skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
The gene belongs to a family of genes encoding proteins containing a BTB domain and several kelch repeats. The BTB domain functions as a protein-protein interaction module, which includes an ability to self-associate or to interact with non-BTB domain-containing proteins. The kelch motif typically occurs in groups of five to seven repeats, and has been found in proteins with diverse functions. Known functions of these family members include transcription regulation, ion channel tetramerization and gating, protein ubiquitination or degradation, and cytoskeleton regulation. The exact function of this family member has yet to be determined.
Stogios, P.J., et al. Genome Biol. 6 (10), R82 (2005) :
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