|Application ||WB, FC, E|
|Other Accession||Q5XI29, Q8BTV2, NP_001129512.1, NP_001136037.1, NP_079087.3|
|Calculated MW||52050 Da|
|Antigen Region||427-455 aa|
|Other Names||Cleavage and polyadenylation specificity factor subunit 7, Cleavage and polyadenylation specificity factor 59 kDa subunit, CFIm59, CPSF 59 kDa subunit, Pre-mRNA cleavage factor Im 59 kDa subunit, CPSF7|
|Target/Specificity||This CPSF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 427-455 amino acids from the C-terminal region of human CPSF7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPSF7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Binds to cleavage and polyadenylation RNA substrates.|
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Provided below are standard protocols that you may find useful for product applications.
CPSF7 is probable a component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3' processing. Binds to cleavage and polyadenylation RNA substrates.
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Lim, J., et al. Cell 125(4):801-814(2006)
Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)
Zhou, Z., et al. Nature 419(6903):182-185(2002)
Ruegsegger, U., et al. J. Biol. Chem. 271(11):6107-6113(1996)
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