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PPP3CC Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PPP3CC Antibody (N-term) AP12168a
    PPP3CC Antibody (N-term) (Cat. #AP12168a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PPP3CC antibody detected the PPP3CC protein (arrow).
  • IHC-P - PPP3CC Antibody (N-term) AP12168a
    PPP3CC Antibody (N-term) (Cat. #AP12168a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPP3CC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48454
Other Accession NP_005596.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 58129 Da
Antigen Region 10-37 aa
Additional Information
Gene ID 5533
Other Names Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, PPP3CC, CALNA3, CNA3
Target/Specificity This PPP3CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human PPP3CC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPP3CC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CALNA3, CNA3
Function Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
Tissue Location Testis.
Research Areas
Citations (0)

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Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).


Liu, Y.J., et al. Obesity (Silver Spring) 18(12):2339-2346(2010)
He, Z.H., et al. Eur. J. Appl. Physiol. 110(4):761-767(2010)
Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)
Kyogoku, C., et al. Psychiatry Res (2010) In press :
Pelak, K., et al. J. Infect. Dis. 201(8):1141-1149(2010)

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$ 295.00
$ 99.00
Cat# AP12168a
(40 western blots)
Availability: In Stock
Bulk Size
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